What is the function of nicotinic acid related to triglycerides?

Nicotinic acid, also known as niacin or vitamin B3, plays a significant role in lipid metabolism. It primarily functions to reduce triglyceride levels in the blood and simultaneously raises high-density lipoprotein (HDL) levels, which is often referred to as "good" cholesterol.

When administered, nicotinic acid decreases the hepatic production of very low-density lipoprotein (VLDL), which is responsible for carrying triglycerides in the bloodstream. By lowering VLDL levels, the overall triglyceride levels in the blood decrease. Additionally, niacin enhances the conversion of low-density lipoprotein (LDL) to HDL, thereby contributing to improved lipid profiles and better cardiovascular health.

This multifaceted action makes nicotinic acid an important component in managing lipid disorders, particularly in patients who may benefit from decreasing triglycerides while also increasing beneficial HDL cholesterol.