What is defined as a failure of two or more organ systems?

The term that describes a failure of two or more organ systems is Multiple Organ Dysfunction Syndrome (MODS). This condition typically arises as a result of a severe illness or injury, where the body’s response leads to progressive failure of multiple organs, ultimately affecting their ability to function properly. MODS can occur in various clinical scenarios such as sepsis, trauma, or pancreatitis, where the inflammatory response and loss of perfusion lead to systemic complications.

In contrast to other options, Catastrophic Organ Failure refers to an acute and severe decline in organ functions but does not specifically denote the involvement of multiple systems. Crisis Intervention generally relates to immediate response tactics used in emergencies but is not a medical term that describes organ system failure. Systemic Inflammatory Response Syndrome (SIRS) describes the body’s inflammatory response to various stressors, but it doesn't necessarily indicate the failure of two or more organs, as it can exist without organ dysfunction. Therefore, MODS is the correct term for acknowledging the simultaneous failure of multiple organ systems.