What impact does being overweight have for individuals with Type 2 diabetes?

Being overweight significantly worsens insulin resistance in individuals with Type 2 diabetes. Insulin resistance occurs when the body's cells do not respond effectively to insulin, which is necessary for glucose uptake from the bloodstream. Excess body fat, particularly visceral fat, secretes various inflammatory substances and hormones that can interfere with the action of insulin. Consequently, the pancreas produces more insulin to overcome this resistance, often leading to higher blood glucose levels and making diabetes management more challenging.

In addition, being overweight is associated with various metabolic disturbances that exacerbate the risk and severity of diabetes-related complications, such as cardiovascular disease, neuropathy, and kidney damage. Thus, losing weight can often lead to improved insulin sensitivity, better blood glucose control, and reduced risk of complications. This underscores the importance of weight management as a crucial aspect of diabetes care and lifestyle modifications for individuals living with Type 2 diabetes.